Mature and young megakaryocytes, mitosis, M-7 leukemia

The Abnormal Mature Megakaryocyte at left center shows an uneven (7) number of nuclei which are unequal in size. The cytoplasm is surrounded by vacuoles. Above it is a small cell with a very high nuclear/cytoplasmic ratio, a very dense nucleus and a prominent Golgi area. It could be an early megakaryocyte, however, the dense nucleus suggests disparity in maturation. At the upper right corner is a small mature megakaryocyte with poor cytoplasmic development. At lower center is an Abnormal Mature Megakaryocyte with few and unequal size nuclei and poorly developed cytoplasmic granulation. Above it is a Young Megakaryocyte in the process of Mitosis. Acute Megakaryocytic Leukemia (M-7). Marrow - 50X


Image ID: 0137-012

sm_cjpLogo.gifCopyright 1995-2010 - Carden Jennings Publishing Co., Ltd. All rights reserved. The material available at this site is for educational purposes only and is NOT intended for any diagnostic, clinically related, or other purpose. Carden Jennings Publishing Co., Ltd., assumes no responsibility for any use or misuse of this material and makes no warranty or representation of any kind with respect to the material available at this site.